Page d'accueil
Le service
Mission
Organisation
Contact
Chiffres et mots-clés
Collaborations
Liens
Activités cliniques
Pharmacologie clinique et pharmacovigilance
Douleur et soins palliatifs
Gérontopharmacologie
Psychopharmacologie
Formation
Enseignement prégradué
Enseignement postgradué
Recherche clinique
Unité d'Investigation Clinique (CRC)
SOP
Documents types
Essais cliniques du service
Liens
Formation continue
PHARMA-FLASH
CAPP-INFO
COMED-INFO
Annuaire
Recherche
Version imprimable
Articles récents
Daali Y, Ancrenaz V, Bosilkovska M, Dayer P, Desmeules J : Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug–drug interaction in HIV patients. Metabolism. 2011;60:1584-9.
L’Huillier AG, K Ing Lorenzini K, Crisinel P-A, Rebsamen MC, Fluss J, Korff CM, Barbe RP, Siegrist C-A, Dayer P, Posfay-Barbe KM, Desmeules J : ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia. Pharmacogenomics. 2011; (in press).
Ing Lorenzini K, Besson M, Daali Y, Salomon D, Dayer P, Desmeules J : A Randomized, Controlled Trial Validates a Peripheral Supra-Additive Antihyperalgesic Effect of a Paracetamol–Ketorolac Combination. Basic Clin Pharmacol Toxicol. 2011;109:357-64.
Ancrenaz V, Daali Y, Fontana P, Besson M, Samer C, Dayer P, Desmeules J : Impact of Genetic Polymorphisms and Drug–Drug Interactions on Clopidogrel and Prasugrel Response Variability. Curr Drug Metab 2010;11:667-77.
Déglon J, Thomas A, Daali Y, Lauer E, Samer C, Desmeules J, Dayer P, Mangin P, Staub C : Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite. J Pharm Biomed Anal 2011; 25:359-67.
Samer C, Daali Y, Wagner M, Hopfgartner G, Eap C, Rebsamen M, Rossier M, Hochstrasser D, Dayer P, Desmeules J : The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone. Brit J Pharmacol 2010; 160: 907-18.
Samer C, Daali Y, Wagner M, Hopfgartner G, Eap C, Rebsamen M, Rossier M, Hochstrasser D, Dayer P, Desmeules J : Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy. Brit J Pharmacol 2010; 160: 919-30.
Ing-Lorenzini K, Desmeules J, Plachta O, Suva D, Dayer P, Peter R : Low-Energy Femoral Fractures Associated with the Long-Term Use of Bisphosphonates (A Case Series from a Swiss University Hospital). Drug Safety 2009; 32: 775-85
.
Kanaan M, Daali Y, Dayer P, Desmeules J. : P-glycoprotein is not involved in the differential oral potency of naloxone and naltrexone. Fundam Clin Pharmacol 2009; 23: 543-8
.
Kanaan M, Daali Y, Dayer P, Desmeules J. : Uptake/efflux transport of tramadol enantiomers and O-desmethyl-tramadol: focus on P-glycoprotein. Basic Clin Pharmacol Toxicol 2009; 105: 199-206
.
Ansermot N, Rebsamen M, Chabert J, Fathi M, Gex-Fabry M, Daali Y, Besson M, Rossier M, Rudaz S, Hochstrasser D, Dayer P, Desmeules J : Influence of ABCB1 Gene Polymorphisms and P-Glycoprotein Activity on Cyclosporine Pharmacokinetics in Peripheral Blood Mononuclear Cells in Healthy Volunteers. Drug Metabolism Letters 2008; 2: 76-82.
Ing-Lorenzini K, Desmeules J, Besson M, Veuthey JL, Dayer P, Dalli Y : Two-dimensional liquid chromatography-ion trap mass spectrometry for the simultaneous determination of ketorolac enantiomers and paracetamol in human plasma: application to a pharmacokinetic study. J Chromatogr A 2009; 1216: 3851-86.
Rollason V, Samer C, Piguet V, Dayer P, Desmeules J : Pharmacogenetics of analgesics: toward the individualization of prescription. Pharmacogenomics 2008; 9: 905-33.
Rebsamen MC, Desmeules J, Daali Y, Chiappe A, Diemand A, Rey C, Chabert J, Dayer P, Hochstrasser D, Rossier MF : The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction. Pharmacogenomics J 2009; 9: 34-41.
Kanaan M, Daali Y, Dayer P, Desmeules J : Lack of interaction of the NMDA receptor antagonists dextromethorphan and dextrorphan with P-glycoprotein. Curr Drug Metab. 2008; 9: 144-51.
Daali Y, Cherkaoui S, Doffey-Lazeyras F, Dayer P, Desmeules J : Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients. J Chromatogr B Analyt Technol Biomed Life Sci 2008; 86: 156-63.
Lutters M, Vogt-Ferrier N : Antibiotic duration for treating uncomplicated, symptomatic lower urinary tract infections in elderly women (Review). Cochrane Database Syst Rev. 2008;3:CD001535
.
Escher M, Daali Y, Chabert J, Hopfgartner G, Dayer P, Desmeules J : Pharmacokinetic and Pharmacodynamic Properties of Buprenorphine After a Single Intravenous Administration in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled. Clin Ther 2007; 29: 1620-31.
Mannion AF, Balagué F, Pellisé F, Cedraschi C : Pain measurements in patients with low back pain. Nat Clin Pract Rheumatol 2007; 3: 610-8.
Ansermot N, Fathi M, Veuthey J-L, Desmeules J, Hochstrasser D, Rudaz S : Quantification of cyclosporine A in peripheral blood mononuclear cells by liquid chromatography-electrospray mass spectrometry using a column-switching approach. J Chromatogr B Analyt Technol Biomed Life Sci. 2007; 857: 92-9.
Piguet V, Cedraschi C, Dumont P, Desmeules J, Allaz A-F, Dayer P : Patients' representations of antidepressants: a clue to nonadherence? Clin J Pain 2007; 23: 669-75.
Luthy C, Cedraschi C, Rutschmann OT, Kossovsky MP, Allaz A-F : Managing postacute hospital care : A case for biopsychosocial needs. J Psychosom Res 2007; 62: 513-9.
Girardin F, Gaspoz J-M : Surveillance de l'intervalle QT chez le patient psychiatrique. Rev Med Suisse 2007; 3: 945-8.
Girardin F, Sztajzel J : Cardiac adverse reactions associated with psychotropic drugs. Dialogues Clin Neurosci 2007 (Poster): 92-5.
Balagué F, Mannion AF, Pellisé F, Cedraschi C: Clinical update: low back pain. Lancet 2007; 369: 726-8.
Girardin F : Membrane transporter proteins: a challenge for CNS drug development. Dialogues Clin Neurosci 2006; 8: 311-21.
Balagué F, Cedraschi C : Radiological examination in low back pain patient:Anxiety of the patient? Anxiety of the therapist? Joint Bone Spine 2006; 73: 508-13.
Ehret GB, Voide K, Gex-Fabry M, Chabert J, Shah D, Broers B, Piguet V, Musset T, Gaspoz J-M, Perrier A, Dayer P, Desmeules JA : Drug-induced long QT syndrome in injection drug users receiving methadone. Arch Intern Med 2006; 166: 1280-7.
Vuilleumier N, Rossier MF, Chiappe A, Degoumois F, Dayer P, Mermillod B, Nicod L, Desmeules J, Hochstrasser D : CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis. Eur J Clin Pharmacol 2006; 62: 423-9.
Henrotin YE, Cedraschi C, Duplan B, Bazin T, Duquesnoy B: Information and low back pain management: a systematic review. Spine 2006 ; 31: E326-34. Review
Airaksinen O, Brox JI, Cedraschi C, Hildebrandt J, Klaber-Moffett J, Kovacs F, Mannion AF, Reis S, Staal JB, Ursin H, Zanoli G : Chapter 4. European guidelines for the management of chronic nonspecific low back pain.
Eur Spine J. 2006 ;15 Suppl 2: S192-300.
Nordin F, Balagué F, Cedraschi C : Nonspecific lower-back pain : surgical versus nonsurgical treatment. Clin Orthop Relat Res. 2006 ; 443: 156-67. Review
Chassot P, Piguet V, Remund C, Luthy C, Cedraschi C : Douleurs chroniques et thérapie cognitivo-comportementale de groupe. Le courrier de l'algologie. 2006: 7-10.
Ehret GB, Deluze C, Dayer P, Desmeules JA : Systemic allergic reaction and diffuse bone pain after exposure to a preparation of betamethasone. Eur J Intern Med 2005; 16: 612-4.
Samer C, Piguet V, Dayer P, Desmeules JA : Polymorphisme génétique et interactions médicamenteuses : leur importance dans le traitement de la douleur [Genetic polymorphism and drug interactions: their importance in the treatment of pain]. Can J Anesth 2005; 52: 806-21.
Girardin F, Pechère-Bertschi A : Traitement de l’hypertension artérielle et interactions médicamenteuses. Rev Med Suisse 2005; 1: 2099-104.
Besson M, Brook P, Chizh BA, Pickering AE : Tactile allodynia in patients with postherpetic neuralgia: Lack of change in skin blood flow upon dynamic stimulation. Pain 2005; 117: 154-61.
Sebo P, Pechere A, Desmeules JA, Dayer P : Treating hypertension: a challenge for the practioner. Rev Med Suisse 2005; 1: 934-8.
Girardin F, Desmeules JA, Dayer P : Sélection d’un médicament dans une classe thérapeutique donnée : l’exemple des «inhibiteurs de l’HMG-CoA réductase». Rev Med Suisse 2005; 1: 949-53.
Gasche Y, Daali Y, Fathi M, Chiappe A, Cottini S, Dayer P, Desmeules J : Codeine intoxication associated with ultrarapid CYP2D6 metabolism. N Engl J Med 2004; 351: 2827-31.
Escher M, Perneger TV, Chevrolet J-C : National questionnaire survey on what influences doctors’ decisions about admission to intensive care. BMJ 2004; 329: 425-30.
Jerdi MC, Daali Y, Oestreicher MK, Cherkaoui S, Dayer P: A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes. J Pharm Biomed Anal. 2004 Sep 3;35(5):1203-12.
Piguet V, Desmeules J, Ehret G, Stoller R, Dayer P: QT interval prolongation in patients on methadone with concomitant drugs. J Clin Psychopharmacol. 2004 Aug;24(4):446-8.
Cedraschi C, Desmeules J, Rapiti E, Baumgartner E, Cohen P, Finckh A, Allaz AF, Vischer TL: Fibromyalgia: a randomised, controlled trial of a treatment programme based on self management. Ann Rheum Dis. 2004 Mar; 63:290-6.
Desmeules J, Piguet V, Dayer P: Développement pharmacologique rationnel des associations d’analgésiques. Rev Rhum (éd. fr.) 2003; 69: hors-série n°1.
Girardin F, Siegenthaler M, De Moerloose P, Desmeules J : Rofecoxib interaction with oral anticoagulant acenocoumarol. Eur J Clin Pharmacol 2003;59:489-90.
Desmeules J, Rollason V, Piguet V, Dayer P : Clinical pharmacology and rationale of analgesic combinations. Eur J Anaesthesiol 2003; 20 (Suppl 28): 7-12.
Desmeules J, Cedraschi C, Rapiti E, Baumgartner E, Finckh A, Cohen P, Dayer P, Vischer TL : Neurophysiologic evidence for a central sensitization in patients with fibromyalgia. Arthritis Rheum 2003; 48: 1420-9.
Bertoli R, Girardin F, Russmann S, Lauterburg BH : Raynaud’s phenomenon induced by drugs acting on neurotransmission : two cases under reboxetine and one under tegaserod. Eur J Clin Pharmacol 2003;58:717.
Cedraschi C, Desmeules J, Luthy C, Allaz A.-F : Aspects psychologiques de la fibromyalgie. Revue du rhumatisme 2003;70:331-6.
Desmeules J, Cedraschi C, Piguet V, Allaz A.-F, Dayer P : Advances with analgesics and non-steroidal inflammatory drugs for the treatment of spinal disorders. Best Pract Res Clin Rheumatol 2002; 16: 105-21.
top
Dernière modification le 01/11/2011
Espace collaboratif
Annonces emploi